HMGB1 Release Induced by EV71 Infection Exacerbates Blood-Brain Barrier Disruption via VE-cadherin Phosphorylation

HMGB1 Release Induced by EV71 Infection Exacerbates Blood-Brain Barrier Disruption via VE-cadherin Phosphorylation

Purpose: EV71 (Enterovirus 71) is a major causative agent of the outbreaks of HFMD (hand, foot, and mouth disease), which is associated with neurological damage caused by permeability disruption of BBB (blood-brain barrier). HMGB1 (high-mobility group box 1) is a widely expressed nuclear protein tha...

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Detalles Bibliográficos
Autores principales: Qiao You, Jing Wu, Ye Liu, Fang Zhang, Na Jiang, Xiaoyan Tian, Yurong Cai, Enhui Yang, Ruining Lyu, Nan Zheng, Deyan Chen, Zhiwei Wu
Formato: Artículo
Lenguaje:English
Publicado: Elsevier 2023-12-01
Colección:Virus Research
Materias:
HMGB1
EV71
BBB
inflammation
VE-cadherin phosphorylation
Acceso en línea:http://www.sciencedirect.com/science/article/pii/S0168170223002022

Internet

http://www.sciencedirect.com/science/article/pii/S0168170223002022

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