A role of TRIM59 in pulmonary hypertension: modulating the protein ubiquitylation modification

Abstract Background Pulmonary hypertension (PH), an infrequent disease, is characterized by excessive pulmonary vascular remodeling and proliferation of pulmonary artery smooth muscle cells (PASMCs). However, its underlying molecular mechanisms remain unclear. Uncovering its molecular mechanisms wil...

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Bibliographic Details
Main Authors: Yingli Liu, Li Zhu, Yue Ming, Zhuhua Wu, Lili Zhang, Qi Chen, Yong Qi
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-023-04712-4