Correlation of exhaled propofol with Narcotrend index and calculated propofol plasma levels in children undergoing surgery under total intravenous anesthesia - an observational study

Correlation of exhaled propofol with Narcotrend index and calculated propofol plasma levels in children undergoing surgery under total intravenous anesthesia - an observational study

Abstract Background Exhaled propofol concentrations correlate with propofol concentrations in adult human blood and the brain tissue of rats, as well as with electroencephalography (EEG) based indices of anesthetic depth. The pharmacokinetics of propofol are however different in children compared to...

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Bibliographic Details
Main Authors: Sebastian Heiderich, Tara Ghasemi, Nils Dennhardt, Robert Sümpelmann, Vanessa Rigterink, Katja Nickel, Oliver Keil, Dietmar Böthig, Christiane E. Beck
Format: Article
Language:English
Published: BMC 2021-05-01
Series:BMC Anesthesiology
Subjects:
Exhaled propofol
Children
TIVA
Pediatric anesthesia
Pharmacokinetic modeling
Online Access:https://doi.org/10.1186/s12871-021-01368-9

Internet

https://doi.org/10.1186/s12871-021-01368-9

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