1,25(OH)2D3 regulates the proangiogenic activity of pericyte through VDR‐mediated modulation of VEGF production and signaling of VEGF and PDGF receptors

1,25(OH)2D3 regulates the proangiogenic activity of pericyte through VDR‐mediated modulation of VEGF production and signaling of VEGF and PDGF receptors

Abstract We have previously demonstrated that the active form of vitamin D (calcitriol; 1,25(OH)2D3) is a potent inhibitor of retinal neovascularization. However, the underlying molecular and cellular mechanisms involved remained poorly understood. Perivascular supporting cells including pericytes (...

Full description

Bibliographic Details
Main Authors: Nasim Jamali, Yong‐Seok Song, Christine M. Sorenson, Nader Sheibani
Format: Article
Language:English
Published: Wiley 2019-07-01
Series:FASEB BioAdvances
Subjects:
angiogenesis
cell adhesion
pericytes
retinal vasculature
signal transduction
vitamin D
Online Access:https://doi.org/10.1096/fba.2018-00067

Internet

https://doi.org/10.1096/fba.2018-00067

Similar Items