Calibrating cardiac electrophysiology models using latent Gaussian processes on atrial manifolds

Abstract Models of electrical excitation and recovery in the heart have become increasingly detailed, but have yet to be used routinely in the clinical setting to guide personalized intervention in patients. One of the main challenges is calibrating models from the limited measurements that can be m...

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Bibliographic Details
Main Authors: Sam Coveney, Caroline H. Roney, Cesare Corrado, Richard D. Wilkinson, Jeremy E. Oakley, Steven A. Niederer, Richard H. Clayton
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-20745-z