Aldosterone Biosynthesis Is Potently Stimulated by Perfluoroalkyl Acids: A Link between Common Environmental Pollutants and Arterial Hypertension

Aldosterone Biosynthesis Is Potently Stimulated by Perfluoroalkyl Acids: A Link between Common Environmental Pollutants and Arterial Hypertension

The large environmental contamination of drinking water by perfluoroalkyl substances (PFAS) markedly increased the plasma levels of pentadecafluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS) in a Northern Italy population with a high prevalence of arterial hypertension and cardiovas...

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Bibliographic Details
Main Authors: Brasilina Caroccia, Teresa Maria Seccia, Giorgia Pallafacchina, Maria Piazza, Ilaria Caputo, Stefania Zamberlan, Rosario Rizzuto, Gian Paolo Rossi
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:International Journal of Molecular Sciences
Subjects:
perfluoroalkyl substances
endocrine disruptors
aldosterone
aldosterone synthase gene expression
arterial hypertension
reactive oxygen species
Online Access:https://www.mdpi.com/1422-0067/24/11/9376

Internet

https://www.mdpi.com/1422-0067/24/11/9376

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