A novel semiautomated method for background activity and biological tumour volume definition to improve standardisation of 18F-FET PET imaging in glioblastoma

Abstract Background Multicentre clinical trials evaluating the role of 18F-Fluoroethyl-l-tyrosine (18F-FET) PET as a diagnostic biomarker in glioma management have highlighted a need for standardised methods of data analysis. 18F-FET uptake normalised against background in the contralateral brain is...

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Bibliographic Details
Main Authors: Caterina Brighi, Simon Puttick, Shenpeng Li, Paul Keall, Katherine Neville, David Waddington, Pierrick Bourgeat, Ashley Gillman, Michael Fay
Format: Article
Language:English
Published: SpringerOpen 2022-02-01
Series:EJNMMI Physics
Subjects:
Online Access:https://doi.org/10.1186/s40658-022-00438-2