Dynein associates with oskar mRNPs and is required for their efficient net plus-end localization in Drosophila oocytes.

In order for eukaryotic cells to function properly, they must establish polarity. The Drosophila oocyte uses mRNA localization to establish polarity and hence provides a genetically tractable model in which to study this process. The spatial restriction of oskar mRNA and its subsequent protein produ...

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Bibliographic Details
Main Authors: Paulomi Sanghavi, Shobha Laxani, Xuan Li, Simon L Bullock, Graydon B Gonsalvez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3823658?pdf=render