Whole mount of adult ear skin as a model to study vascular malformations
Abstract Background Genetic analysis in human patients has linked mutations in PIK3CA, the catalytic subunit of PI‐3′Kinase, to sporadic incidences of vascular malformations. Methods We have developed a mouse model with inducible and endothelial‐specific expression of PIK3CAH1047R, resulting in the...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-08-01
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| Series: | Animal Models and Experimental Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ame2.12343 |