The effects of dipeptidyl peptidase-4 on cardiac fibrosis in pressure overload-induced heart failure

The effects of dipeptidyl peptidase-4 on cardiac fibrosis in pressure overload-induced heart failure

Dipeptidyl peptidase-4 (DPP-4) inhibitors are hypoglycemic agents. DPP-4 inhibitor has cardioprotective effects after transverse aortic constriction (TAC), but role of DPP-4 on cardiac fibrosis after TAC is not well known. Our aim was to determine the effects of DPP-4 on cardiac fibrosis in murine T...

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Bibliographic Details
Main Authors: Masanori Hirose, Hiroyuki Takano, Hiroshi Hasegawa, Hiroyuki Tadokoro, Naoko Hashimoto, Genzo Takemura, Yoshio Kobayashi
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Journal of Pharmacological Sciences
Subjects:
cardiac fibrosis
Cardiac hypertrophy
Collagen
DPP-4
Heart failure
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861317301913

Internet

http://www.sciencedirect.com/science/article/pii/S1347861317301913

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