Butyrate Prevents TGF-β1-Induced Alveolar Myofibroblast Differentiation and Modulates Energy Metabolism

Butyrate Prevents TGF-β1-Induced Alveolar Myofibroblast Differentiation and Modulates Energy Metabolism

Idiopathic pulmonary fibrosis (IPF) is a serious lung disease characterized by excessive collagen matrix deposition and extracellular remodeling. Signaling pathways mediated by fibrotic cytokine transforming growth factor β1 (TGF-β1) make important contributions to pulmonary fibrosis, but it remains...

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Bibliographic Details
Main Authors: Hyo Yeong Lee, Somi Nam, Mi Jeong Kim, Su Jung Kim, Sung Hoon Back, Hyun Ju Yoo
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Metabolites
Subjects:
short chain fatty acids
butyrate
TGF-β1
pulmonary fibrosis
myofibroblast differentiation
mitochondria
Online Access:https://www.mdpi.com/2218-1989/11/5/258

Internet

https://www.mdpi.com/2218-1989/11/5/258

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