Micro-hydrogel injectables that deliver effective CAR-T immunotherapy against 3D solid tumor spheroids

Micro-hydrogel injectables that deliver effective CAR-T immunotherapy against 3D solid tumor spheroids

Chimeric antigen receptor (CAR-) T cells are revolutionizing cancer treatment, as a direct result of their clinical impact on the treatment of hematological malignancies. However for solid tumors, CAR-T cell therapeutic efficacy remains limited, primarily due to the complex immunosuppressive tumor m...

Full description

Bibliographic Details
Main Authors: Anisha B. Suraiya, Vera J. Evtimov, Vinh X. Truong, Richard L. Boyd, John S. Forsythe, Nicholas R. Boyd
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Translational Oncology
Subjects:
Microgels
Cell encapsulation
Immunotherapy
CAR-T cells
Cell delivery
Tumor spheroids
Online Access:http://www.sciencedirect.com/science/article/pii/S193652332200136X

Internet

http://www.sciencedirect.com/science/article/pii/S193652332200136X

Similar Items