The Free-Energy Landscape of a Mechanically Bistable DNA Origami

Molecular simulations using coarse-grained models allow the structure, dynamics and mechanics of DNA origamis to be comprehensively characterized. Here, we focus on the free-energy landscape of a jointed DNA origami that has been designed to exhibit two mechanically stable states and for which a bis...

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Bibliographic Details
Main Authors: Chak Kui Wong, Jonathan P. K. Doye
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Applied Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3417/12/12/5875