ATM and ATR Expression Potentiates HBV Replication and Contributes to Reactivation of HBV Infection upon DNA Damage

ATM and ATR Expression Potentiates HBV Replication and Contributes to Reactivation of HBV Infection upon DNA Damage

Chronic hepatitis B virus infection (CHB) caused by the hepatitis B virus (HBV) is one of the most common viral infections in the world. Reactivation of HBV infection is a life-threatening condition observed in patients with CHB receiving chemotherapy or other medications. Although HBV reactivation...

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Bibliographic Details
Main Authors: Anastasiya Kostyusheva, Sergey Brezgin, Ekaterina Bayurova, Ilya Gordeychuk, Maria Isaguliants, Irina Goptar, Felix Urusov, Anastasiya Nikiforova, Elena Volchkova, Dmitry Kostyushev, Vladimir Chulanov
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Viruses
Subjects:
hbv reactivation
replication
dna damage
atm
atr
phosphorylated h2ax
yh2ax
shrna
crispr/cas9
crispra
dcas9
Online Access:https://www.mdpi.com/1999-4915/11/11/997

Internet

https://www.mdpi.com/1999-4915/11/11/997

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