Identification of a mutation associated with fatal Foal Immunodeficiency Syndrome in the Fell and Dales pony.

Identification of a mutation associated with fatal Foal Immunodeficiency Syndrome in the Fell and Dales pony.

The Fell and Dales are rare native UK pony breeds at risk due to falling numbers, in-breeding, and inherited disease. Specifically, the lethal Mendelian recessive disease Foal Immunodeficiency Syndrome (FIS), which manifests as B-lymphocyte immunodeficiency and progressive anemia, is a substantial t...

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Bibliographic Details
Main Authors: Laura Y Fox-Clipsham, Stuart D Carter, Ian Goodhead, Neil Hall, Derek C Knottenbelt, Paul D F May, William E Ollier, June E Swinburne
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-07-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3131283?pdf=render

Internet

http://europepmc.org/articles/PMC3131283?pdf=render

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