Interplay of Stem Cell Characteristics, EMT, and Microtentacles in Circulating Breast Tumor Cells

Metastasis, not the primary tumor, is responsible for the majority of breast cancer-related deaths. Emerging evidence indicates that breast cancer stem cells (CSCs) and the epithelial-to-mesenchymal transition (EMT) cooperate to produce circulating tumor cells (CTCs) that are highly competent for me...

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Bibliographic Details
Main Authors: Stuart Martin, Monica Charpentier
Format: Article
Language:English
Published: MDPI AG 2013-11-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/5/4/1545