Interplay of Stem Cell Characteristics, EMT, and Microtentacles in Circulating Breast Tumor Cells
Metastasis, not the primary tumor, is responsible for the majority of breast cancer-related deaths. Emerging evidence indicates that breast cancer stem cells (CSCs) and the epithelial-to-mesenchymal transition (EMT) cooperate to produce circulating tumor cells (CTCs) that are highly competent for me...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2013-11-01
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Series: | Cancers |
Subjects: | |
Online Access: | http://www.mdpi.com/2072-6694/5/4/1545 |