Luseogliflozin and caloric intake restriction increase superoxide dismutase 2 expression, promote antioxidative effects, and attenuate aortic endothelial dysfunction in diet‐induced obese mice

Luseogliflozin and caloric intake restriction increase superoxide dismutase 2 expression, promote antioxidative effects, and attenuate aortic endothelial dysfunction in diet‐induced obese mice

Abstract Aims/Introduction The mechanisms underlying the effect of sodium‐glucose cotransporter 2 (SGLT2) inhibitors on aortic endothelial dysfunction in diet‐induced obesity are not clearly understood. This study investigated whether SGLT2 inhibition by luseogliflozin improved free fatty acid (FFA)...

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書目詳細資料
Main Authors: Shigeru Kawade, Kazuma Ogiso, Sigfrid Casmir Shayo, Takahiko Obo, Aiko Arimura, Hiroshi Hashiguchi, Takahisa Deguchi, Yoshihiko Nishio
格式: Article
語言:English
出版: Wiley 2023-04-01
叢編:Journal of Diabetes Investigation
主題:
Aortic endothelial dysfunction
Oxidative stress
Sodium‐glucose cotransporter 2
在線閱讀:https://doi.org/10.1111/jdi.13981

因特網

https://doi.org/10.1111/jdi.13981

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