A mathematical model for the onset of avascular tumor growth in response to the loss of p53 function
We present a mathematical model for the formation of an avascular tumor based on the loss by gene mutation of the tumor suppressor function of p53. The wild type p53 protein regulates apoptosis, cell expression of growth factor and matrix metalloproteinase, which are regulatory functions that many m...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2006-01-01
|
| Series: | Cancer Informatics |
| Online Access: | http://la-press.com/article.php?article_id=103 |