Ethnic Differences in the Frequency of CFTR Gene Mutations in Populations of the European and North Caucasian Part of the Russian Federation

Ethnic Differences in the Frequency of CFTR Gene Mutations in Populations of the European and North Caucasian Part of the Russian Federation

Cystic fibrosis (CF) is a common monogenic disease caused by pathogenic variants in the CFTR gene. The distribution and frequency of CFTR variants vary in different countries and ethnic groups. The spectrum of pathogenic variants of the CFTR gene was previously studied in more than 1,500 CF patients...

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Bibliographic Details
Main Authors: Nika Petrova, Natalia Balinova, Andrey Marakhonov, Tatyana Vasilyeva, Nataliya Kashirskaya, Varvara Galkina, Evgeniy Ginter, Sergey Kutsev, Rena Zinchenko
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Genetics
Subjects:
allelic polymorphism
CFTR gene variants
population differences
ethnic diversity
European and North Caucasian part of Russia
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.678374/full

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https://www.frontiersin.org/articles/10.3389/fgene.2021.678374/full

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