Monitoring regulation of DNA repair activities of cultured cells in-gel using the comet assay

Base excision repair (BER) is the predominant cellular mechanism by which human cells repair DNA base damage, sites of base loss and DNA single strand breaks of various complexity, that are generated in their thousands in every human cell per day as a consequence of cellular metabolism and exogenous...

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Bibliographic Details
Main Authors: Jason Luke Parsons, Catherine Marie Nickson
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00232/full