Characterization of the genetic variation and evolutionary divergence of the CLEC18 family

Characterization of the genetic variation and evolutionary divergence of the CLEC18 family

Abstract Background The C-type lectin family 18 (CLEC18) with lipid and glycan binding capabilities is important to metabolic regulation and innate immune responses against viral infection. However, human CLEC18 comprises three paralogous genes with highly similar sequences, making it challenging to...

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Bibliographic Details
Main Authors: Che-Mai Chang, Wei-Chiao Chang, Shie‐Liang Hsieh
Format: Article
Language:English
Published: BMC 2024-05-01
Series:Journal of Biomedical Science
Subjects:
CLEC18
CAP/SCP/TAPS domain
CTLD
Long-read sequencing
Human pangenome
Single amino acid variant
Online Access:https://doi.org/10.1186/s12929-024-01034-5

Internet

https://doi.org/10.1186/s12929-024-01034-5

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