Mechanical basis and topological routes to cell elimination

Cell layers eliminate unwanted cells through the extrusion process, which underlines healthy versus flawed tissue behaviors. Although several biochemical pathways have been identified, the underlying mechanical basis including the forces involved in cellular extrusion remains largely unexplored. Uti...

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Bibliographic Details
Main Authors: Siavash Monfared, Guruswami Ravichandran, José Andrade, Amin Doostmohammadi
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-04-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/82435