KA-Search, a method for rapid and exhaustive sequence identity search of known antibodies

Abstract Antibodies with similar amino acid sequences, especially across their complementarity-determining regions, often share properties. Finding that an antibody of interest has a similar sequence to naturally expressed antibodies in healthy or diseased repertoires is a powerful approach for the...

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Bibliographic Details
Main Authors: Tobias H. Olsen, Brennan Abanades, Iain H. Moal, Charlotte M. Deane
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-38108-7