Comparative Analysis of Immune Checkpoint Molecules and Their Potential Role in the Transmissible Tasmanian Devil Facial Tumor Disease

Comparative Analysis of Immune Checkpoint Molecules and Their Potential Role in the Transmissible Tasmanian Devil Facial Tumor Disease

Immune checkpoint molecules function as a system of checks and balances that enhance or inhibit immune responses to infectious agents, foreign tissues, and cancerous cells. Immunotherapies that target immune checkpoint molecules, particularly the inhibitory molecules programmed cell death 1 and cyto...

Full description

Bibliographic Details
Main Authors: Andrew S. Flies, Nicholas B. Blackburn, Alan Bruce Lyons, John D. Hayball, Gregory M. Woods
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Immunology
Subjects:
devil
transmissible tumor
cosignaling immunotherapy
checkpoint blockade
wild immunity
allograft
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00513/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.00513/full

Similar Items