Dynamic planar scintigraphy for the rapid kinetic measurement of myocardial 123I-MIBG turnover can identify Lewy body disease

Dynamic planar scintigraphy for the rapid kinetic measurement of myocardial 123I-MIBG turnover can identify Lewy body disease

Abstract Background Using two static scans for 123I-meta-iodobenzyl-guanidine (123I-MIBG) myocardial scintigraphy ignores the dynamic response from vesicular trapping in nerve terminals. Moreover, the long pause between scans is impractical for patients with Lewy body diseases (LBDs). Here, we optim...

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Bibliographic Details
Main Authors: Yoshitaka Kumakura, Yuji Shimizu, Masatsugu Hariu, Ken-ichi Ichikawa, Norihito Yoshida, Masato Suzuki, Satoru Oji, Shinya Narukawa, Haruo Yoshimasu, Kyoichi Nomura
Format: Article
Language:English
Published: SpringerOpen 2021-12-01
Series:EJNMMI Research
Subjects:
123I-MIBG
Kinetic modelling
Turnover
Lewy body diseases
Myocardial sympathetic nerves
Online Access:https://doi.org/10.1186/s13550-021-00864-w

Internet

https://doi.org/10.1186/s13550-021-00864-w

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