Meprin β regulates osteopontin-signaling in ischemia/reperfusion-induced kidney injury

Abstract Background Meprin metalloproteases have been implicated in the pathology of ischemia/reperfusion (IR) induced kidney injury. Meprin β proteolytically processes several mediators of cell signaling pathways involved in apoptosis and extracellular matrix metabolism. We previously showed that m...

Full description

Bibliographic Details
Main Authors: Faihaa Ahmed, Shaymaa Abousaad, Ayman Abouzeid, Christine Adhiambo, Elimelda Moige Ongeri
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Nephrology
Subjects:
Online Access:https://doi.org/10.1186/s12882-025-03995-7