Improving CLIP-seq data analysis by incorporating transcript information

Abstract Background Current peak callers for identifying RNA-binding protein (RBP) binding sites from CLIP-seq data take into account genomic read profiles, but they ignore the underlying transcript information, that is information regarding splicing events. So far, there are no studies available th...

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Bibliographic Details
Main Authors: Michael Uhl, Van Dinh Tran, Rolf Backofen
Format: Article
Language:English
Published: BMC 2020-12-01
Series:BMC Genomics
Subjects:
Online Access:https://doi.org/10.1186/s12864-020-07297-0