Modulation of Guanylate Cyclase Activating Protein 1 (GCAP1) Dimeric Assembly by Ca<sup>2+</sup> or Mg<sup>2+</sup>: Hints to Understand Protein Activity
The guanylyl cyclase-activating protein 1, GCAP1, activates or inhibits retinal guanylyl cyclase (retGC) depending on cellular Ca<sup>2+</sup> concentrations. Several point mutations of GCAP1 have been associated with impaired calcium sensitivity that eventually triggers progressive reti...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-10-01
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Series: | Biomolecules |
Subjects: | |
Online Access: | https://www.mdpi.com/2218-273X/10/10/1408 |