Orientia tsutsugamushi subverts dendritic cell functions by escaping from autophagy and impairing their migration.

Orientia tsutsugamushi subverts dendritic cell functions by escaping from autophagy and impairing their migration.

BACKGROUND: Dendritic cells (DCs) are the most potent antigen-presenting cells that link innate and adaptive immune responses, playing a pivotal role in triggering antigen-specific immunity. Antigen uptake by DCs induces maturational changes that include increased surface expression of major histoco...

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Bibliographic Details
Main Authors: Ji-Hye Choi, Taek-Chin Cheong, Na-Young Ha, Youngho Ko, Chung-Hyun Cho, Ju-Hong Jeon, Insuk So, In-Kyu Kim, Myung-Sik Choi, Ik-Sang Kim, Nam-Hyuk Cho
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3536799?pdf=render

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http://europepmc.org/articles/PMC3536799?pdf=render

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