A novel f-divergence based generative adversarial imputation method for scRNA-seq data analysis.

Comprehensive analysis of single-cell RNA sequencing (scRNA-seq) data can enhance our understanding of cellular diversity and aid in the development of personalized therapies for individuals. The abundance of missing values, known as dropouts, makes the analysis of scRNA-seq data a challenging task....

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Bibliographic Details
Main Authors: Tong Si, Zackary Hopkins, John Yanev, Jie Hou, Haijun Gong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0292792