Triggering of Suicidal Erythrocyte Death by Pazopanib

Triggering of Suicidal Erythrocyte Death by Pazopanib

Background/Aims: The multi-targeted kinase inhibitor pazopanib, a drug employed for the treatment of a wide variety of malignancies, has previously been shown to trigger apoptosis. Similar to apoptosis of nucleated cells, erythrocytes may enter suicidal death or eryptosis, characterized by cell shri...

Full description

Bibliographic Details
Main Authors: Elena Signoretto, Jens Zierle, Rosi Bissinger, Michela Castagna, Elena Bossi, Florian Lang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-03-01
Series:Cellular Physiology and Biochemistry
Subjects:
Phosphatidylserine
Cell volume
Eryptosis
Ionomycin
Calcium
Online Access:http://www.karger.com/Article/FullText/443045

Internet

http://www.karger.com/Article/FullText/443045

Similar Items