Interplay between endocannabinoids and dopamine in the basal ganglia: implications for pain in Parkinson’s disease

Abstract Pain is a complex phenomenon, and basal ganglia circuitry integrates many aspects of pain including motor, emotional, autonomic, and cognitive responses. Perturbations in dopamine (DA) signaling are implicated in the pathogenesis of chronic pain due to its involvement in both pain perceptio...

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Bibliographic Details
Main Authors: Maria Mancini, Alessandra Calculli, Deborah Di Martino, Antonio Pisani
Format: Article
Language:English
Published: BMC 2024-05-01
Series:Journal of Anesthesia, Analgesia and Critical Care
Subjects:
Online Access:https://doi.org/10.1186/s44158-024-00169-z