Splicing signature database development to delineate cancer pathways using literature mining and transcriptome machine learning

Splicing signature database development to delineate cancer pathways using literature mining and transcriptome machine learning

Alternative splicing (AS) events modulate certain pathways and phenotypic plasticity in cancer. Although previous studies have computationally analyzed splicing events, it is still a challenge to uncover biological functions induced by reliable AS events from tremendous candidates. To provide essent...

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Bibliographic Details
Main Authors: Kyubin Lee, Daejin Hyung, Soo Young Cho, Namhee Yu, Sewha Hong, Jihyun Kim, Sunshin Kim, Ji-Youn Han, Charny Park
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Text-mining
Machine-learning
Alternative splicing
Tumor transcriptome
Database
Gene signature
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037023000983

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http://www.sciencedirect.com/science/article/pii/S2001037023000983

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