Antioxidant Effect of Propofol in Gliomas and Its Association With Divalent Metal Transporter 1

Antioxidant Effect of Propofol in Gliomas and Its Association With Divalent Metal Transporter 1

BackgroundOxidative stress enhances tumor invasion and metastasis in brain cancer. The activation of divalent metal transporter 1 (DMT1), which is regulated by glutamate receptors, can result in the increase of oxidative stress and risk of cancer development. Propofol, an anesthetic with antioxidant...

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Bibliographic Details
Main Authors: Chenyi Yang, Zhengyuan Xia, Tang Li, Yimeng Chen, Mingshu Zhao, Yi Sun, Ji Ma, Yi Wu, Xinyue Wang, Peng Wang, Haiyun Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Oncology
Subjects:
glioma
propofol
divalent metal transporter 1
α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor
oxidative stress
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.590931/full

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https://www.frontiersin.org/articles/10.3389/fonc.2020.590931/full

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