Targeting the Wnt/β-catenin signaling pathway in cancer

Abstract The aberrant Wnt/β-catenin signaling pathway facilitates cancer stem cell renewal, cell proliferation and differentiation, thus exerting crucial roles in tumorigenesis and therapy response. Accumulated investigations highlight the therapeutic potential of agents targeting Wnt/β-catenin sign...

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Bibliographic Details
Main Authors: Ya Zhang, Xin Wang
Format: Article
Language:English
Published: BMC 2020-12-01
Series:Journal of Hematology & Oncology
Subjects:
Online Access:https://doi.org/10.1186/s13045-020-00990-3