Targeting the Wnt/β-catenin signaling pathway in cancer
Abstract The aberrant Wnt/β-catenin signaling pathway facilitates cancer stem cell renewal, cell proliferation and differentiation, thus exerting crucial roles in tumorigenesis and therapy response. Accumulated investigations highlight the therapeutic potential of agents targeting Wnt/β-catenin sign...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-12-01
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Series: | Journal of Hematology & Oncology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13045-020-00990-3 |