The neuropsychopharmacology of acetyl-L-carnitine (LAC): basic, translational and therapeutic implications

The neuropsychopharmacology of acetyl-L-carnitine (LAC): basic, translational and therapeutic implications

Abstract Mitochondrial metabolism can contribute to nuclear histone acetylation among other epigenetic mechanisms. A central aspect of this signaling pathway is acetyl-L-carnitine (LAC), a pivotal mitochondrial metabolite best known for its role in fatty acid oxidation. Work from our and other group...

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Bibliographic Details
Main Authors: Benedetta Bigio, Shofiul Azam, Aleksander A. Mathé, Carla Nasca
Format: Article
Language:English
Published: Springer 2024-01-01
Series:Discover Mental Health
Subjects:
Histone acetylation
Glutamate
Hippocampus
Depression
Cognition
Online Access:https://doi.org/10.1007/s44192-023-00056-z

Internet

https://doi.org/10.1007/s44192-023-00056-z

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