Sensing of p53 and EGFR Biomarkers Using High Efficiency SERS Substrates

Sensing of p53 and EGFR Biomarkers Using High Efficiency SERS Substrates

In this paper we describe a method for the determination of protein concentration using Surface Enhanced Raman Resonance Scattering (SERRS) immunoassays. We use two different Raman active linkers, 4-aminothiophenol and 6-mercaptopurine, to bind to a high sensitivity SERS substrate and investigate th...

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Bibliographic Details
Main Authors: Peter Owens, Nigel Phillipson, Jayakumar Perumal, Gerard M. O’Connor, Malini Olivo
Format: Article
Language:English
Published: MDPI AG 2015-10-01
Series:Biosensors
Subjects:
Raman spectroscopy
protein sensing
surface-enhanced Raman scattering
biomarker
Online Access:http://www.mdpi.com/2079-6374/5/4/664

Internet

http://www.mdpi.com/2079-6374/5/4/664

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