Rational Formulation of targeted ABT-737 nanoparticles by self-assembled polypeptides and designed peptides
Here we present the development of nanoparticles (NPs) formulations specifically designed for targeting the antiapoptotic Bcl-2 proteins on the outer membrane of mitochondria with the drug agent ABT-737. The NPs which are self-assembled by the natural polypeptide poly gamma glutamic acid (ϒPGA) and...
Main Authors: | Polina Aibinder, Ifat Cohen-Erez, Hanna Rapaport |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2024-02-01
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Series: | Heliyon |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844024021261 |
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