Comparative Use of Contralateral and Sham-Operated Controls Reveals Traces of a Bilateral Genetic Response in the Rat Brain after Focal Stroke

Comparative Use of Contralateral and Sham-Operated Controls Reveals Traces of a Bilateral Genetic Response in the Rat Brain after Focal Stroke

Ischemic stroke is a multifactorial disease with a complex etiology and global consequences. Model animals are widely used in stroke studies. Various controls, either brain samples from sham-operated (SO) animals or symmetrically located brain samples from the opposite (contralateral) hemisphere (CH...

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Bibliographic Details
Main Authors: Ivan B. Filippenkov, Julia A. Remizova, Alina E. Denisova, Vasily V. Stavchansky, Ksenia D. Golovina, Leonid V. Gubsky, Svetlana A. Limborska, Lyudmila V. Dergunova
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:International Journal of Molecular Sciences
Subjects:
tMCAO
RNA-Seq
contralateral hemisphere of the rat brain
sham-operated rats
gene expression
transhemispheric differences
Online Access:https://www.mdpi.com/1422-0067/23/13/7308

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https://www.mdpi.com/1422-0067/23/13/7308

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