Direct antigen presentation is the canonical pathway of cytomegalovirus CD8 T-cell priming regulated by balanced immune evasion ensuring a strong antiviral response

Direct antigen presentation is the canonical pathway of cytomegalovirus CD8 T-cell priming regulated by balanced immune evasion ensuring a strong antiviral response

CD8 T cells are important antiviral effectors in the adaptive immune response to cytomegaloviruses (CMV). Naïve CD8 T cells can be primed by professional antigen-presenting cells (pAPCs) alternatively by “direct antigen presentation” or “antigen cross-presentation”. In the case of direct antigen pre...

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Bibliographic Details
Main Authors: Julia K. Büttner, Sara Becker, Annette Fink, Melanie M. Brinkmann, Rafaela Holtappels, Matthias J. Reddehase, Niels A. Lemmermann
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Immunology
Subjects:
CD8 T cell response
m152/gp40
antigen presentation
antigen cross-presentation
antigen presenting cell (APC)
murine cytomegalovirus (mCMV)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1272166/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1272166/full

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