Mechanism of expression regulation of head-to-head overlapping protein-coding genes INO80E and HIRIP3

Abstract Although the existence of overlapping protein-coding genes in eukaryotic genomes is known for decades, their role in regulating expression remains far from fully understood. Here, the mechanism regulating the expression of head-to-head overlapping genes, a pair of INO80E and HIRIP3 genes is...

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Bibliographic Details
Main Authors: Natalia Ryczek, Aneta Łyś, Elżbieta Wanowska, Joanna Kozłowska-Masłoń, Izabela Makałowska
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-07815-4