Chiral Building Blocks: Enantioselective Syntheses of Benzyloxymethyl Phenyl Propionic Acids

Chiral Building Blocks: Enantioselective Syntheses of Benzyloxymethyl Phenyl Propionic Acids

The synthesis of (2S)-2-benzyloxymethyl-3-(2-fluoro-4-methoxyphenyl)- propionic acid, (2S)-2-benzyloxymethyl-3-(2-fluoro-4-methylphenyl)propionic acid and (2S)-2-benzyl-oxymethyl-3-(2,4-dimethylphenyl)propionic acid has been achieved by TiCl4 mediated alkylation of the corresponding (4R)-4-benzyl-3-...

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Bibliographic Details
Main Authors: Rustum S. Boyce, Jonathan M. White, Andrew M. Bray, Ian W. James, Craig S. Sheehan, Thao Nguyen, Sharon T. Marino, Beata M. Krywult, Daniel A. Huggins, Peter G. Griffiths, Neil Choi, Danuta Stachurska-Buczek, Jack G. Parsons
Format: Article
Language:English
Published: MDPI AG 2004-05-01
Series:Molecules
Subjects:
TiCl4
stereoselective
alkylation
benzyloxymethylphenylpropionic acids.
Online Access:http://www.mdpi.com/1420-3049/9/6/449/

Internet

http://www.mdpi.com/1420-3049/9/6/449/

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