Current advancements of modelling schizophrenia using patient-derived induced pluripotent stem cells

Abstract Schizophrenia (SZ) is a severe psychiatric disorder, with a prevalence of 1–2% world-wide and substantial health- and social care costs. The pathology is influenced by both genetic and environmental factors, however the underlying cause still remains elusive. SZ has symptoms including delus...

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Bibliographic Details
Main Authors: Ugne Dubonyte, Andrea Asenjo-Martinez, Thomas Werge, Kasper Lage, Agnete Kirkeby
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Acta Neuropathologica Communications
Online Access:https://doi.org/10.1186/s40478-022-01460-2