Structural modification of berberine alkaloid and their hypoglycemic activity

Berberine (BBR), a major active component of natural plant product, has recently been demonstrated to be clinically effective in alleviating type 2 diabetes mellitus (T2DM). In this study, BBR and 8-alkylberberine were successively halogenated with bromine, iodine, chlorine under various conditions....

Full description

Bibliographic Details
Main Authors: Yangping Ding, Xiaoli Ye, Jiaying Zhu, Xiaokang Zhu, Xuegang Li, Bingcan Chen
Format: Article
Language:English
Published: Elsevier 2014-03-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464614000577