Targeting PDZ domains as potential treatment for viral infections, neurodegeneration and cancer

Targeting PDZ domains as potential treatment for viral infections, neurodegeneration and cancer

Abstract The interaction between proteins is a fundamental event for cellular life that is generally mediated by specialized protein domains or modules. PDZ domains are the largest class of protein–protein interaction modules, involved in several cellular pathways such as signal transduction, cell–c...

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Bibliographic Details
Main Authors: Caterina Nardella, Lorenzo Visconti, Francesca Malagrinò, Livia Pagano, Marianna Bufano, Marianna Nalli, Antonio Coluccia, Giuseppe La Regina, Romano Silvestri, Stefano Gianni, Angelo Toto
Format: Article
Language:English
Published: BMC 2021-10-01
Series:Biology Direct
Subjects:
Inhibitors
Small molecules
Protein–protein interactions
Online Access:https://doi.org/10.1186/s13062-021-00303-9

Internet

https://doi.org/10.1186/s13062-021-00303-9

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