TRIMming Type I Interferon-Mediated Innate Immune Response in Antiviral and Antitumor Defense

The tripartite motif (TRIM) family comprises at least 80 members in humans, with most having ubiquitin or SUMO E3 ligase activity conferred by their N-terminal RING domain. TRIMs regulate a wide range of processes in ubiquitination- or sumoylation-dependent manners in most cases, and fewer as adapto...

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Bibliographic Details
Main Authors: Ling Wang, Shunbin Ning
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/13/2/279