Predictive analytics identifies key factors driving hyperalgesic priming of muscle sensory neurons

Predictive analytics identifies key factors driving hyperalgesic priming of muscle sensory neurons

Hyperalgesic priming, a form of neuroplasticity induced by inflammatory mediators, in peripheral nociceptors enhances the magnitude and duration of action potential (AP) firing to future inflammatory events and can potentially lead to pain chronification. The mechanisms underlying the development of...

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Bibliographic Details
Main Authors: Sridevi Nagaraja, Shivendra G. Tewari, Jaques Reifman
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Neuroscience
Subjects:
musculoskeletal pain
nociceptor
ion channels
computational analysis
action potential
hyperalgesic priming
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2023.1254154/full

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https://www.frontiersin.org/articles/10.3389/fnins.2023.1254154/full

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