Negative regulation of thyroid adenoma-associated protein (THADA) in the cardiac glycoside-induced anti-cancer effect

Negative regulation of thyroid adenoma-associated protein (THADA) in the cardiac glycoside-induced anti-cancer effect

Abstract Cardiac glycosides, known as inhibitors of Na+,K+-ATPase, have anti-cancer effects such as suppression of cancer cell proliferation and induction of cancer cell death. Here, we examined the signaling pathway elicited by cardiac glycosides in the human hepatocellular carcinoma HepG2 cells an...

Full description

Bibliographic Details
Main Authors: Mizuki Katoh, Takuto Fujii, Yoshiaki Tabuchi, Takahiro Shimizu, Hideki Sakai
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Journal of Physiological Sciences
Subjects:
Thyroid adenoma-associated protein
L-type amino acid transporter 1
Na+,K+-ATPase
Cardiac glycoside
Cancer cells
Online Access:https://doi.org/10.1186/s12576-024-00914-7

Internet

https://doi.org/10.1186/s12576-024-00914-7

Similar Items