The effect of emicizumab and bypassing agents in patients with hemophilia – An in vitro study

Abstract Background Emicizumab is a nonfactor replacement therapy for hemophilia A (HA) and is a bispecific monoclonal antibody mimicking factor VIII by binding both factors IXa and X. Although it reduces the frequency of bleeding episodes, there is still need for bypassing agents in case of breakth...

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Bibliographic Details
Main Authors: Nina Haagenrud Schultz, Heidi Glosli, Stine Bjørnsen, Pål Andre Holme
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Research and Practice in Thrombosis and Haemostasis
Subjects:
Online Access:https://doi.org/10.1002/rth2.12561