An Electrochemical Synthesis of Functionalized Arylpyrimidines from 4-Amino-6-Chloropyrimidines and Aryl Halides

An Electrochemical Synthesis of Functionalized Arylpyrimidines from 4-Amino-6-Chloropyrimidines and Aryl Halides

A range of novel 4-amino-6-arylpyrimidines has been prepared under mild conditions by an electrochemical reductive cross-coupling between 4-amino-6-chloro-pyrimidines and functionalized aryl halides. The process, which employs a sacrificial iron anode in conjunction with a nickel(II) catalyst, allow...

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Bibliographic Details
Main Authors: Eric Léonel, Erwan Le Gall, Stéphane Sengmany
Format: Article
Language:English
Published: MDPI AG 2011-06-01
Series:Molecules
Subjects:
cross-coupling
electrosynthesis
functionalized pyrimidines
nickel catalysis
sacrificial anode process
Online Access:http://www.mdpi.com/1420-3049/16/7/5550/

Internet

http://www.mdpi.com/1420-3049/16/7/5550/

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